Crohn's disease belongs to the group of chronic inflammatory gastric diseases and is characterized by constant inflammation of the entire gastrointestinal tract. These may occur from the mouth to the anus, but are most frequently observed in the lower intestine and around the transition to the colon. The US specialist for intestines, Burrill Bernard Crohn, gave the disease its name.
In contrast to ulcerative colitis, all layers of the intestinal wall are inflamed in Crohn's disease. As a result, these thicken as the disease progresses. The so-called segmental occurrence of the inflammatory focus is striking. This means that near ill parts, healthy areas are present. The constant inflammation processes lead to narrowing (stenoses) and fistulas of the intestine.
Fistulas are new inflammatory processes, e.g. between different intestinal sections. Fistulas occur frequently in the region of the anus. Crohn's disease affects mainly young people between the ages of 15 and 35. However, it can also occur in later years.